Bottle Size: 90 caps
Pill Size: 100 mg
5-HTP – enhances serotonin production*
• Increases serotonin levels for sleep enhancement, decreased sugar cravings, and better stress management*
• Can be taken with meals without competing with other amino acids
• Includes vitamin B6 for optimal activity
• Made without flowing agents that can inhibit bioavailability
Thorne Research 5-HTP Benefits
5-Hydroxytryptophan (5-HTP) is the intermediate metabolite produced when the body initiates the process of converting the essential amino acid L-tryptophan to serotonin. Serotonin levels in the body are associated with the regulation of sleep, mood, aggression, appetite, temperature, sexual behavior, and pain sensation.*
Supplementing with 5-HTP to facilitate serotonin production is preferable to supplementing with L-tryptophan because, unlike L-tryptophan, 5-HTP cannot be shunted into niacin or protein production.* Supplementation with 5-HTP bypasses the conversion of L-tryptophan into 5-HTP by the enzyme tryptophan hydroxylase, the rate-limiting step in the synthesis of serotonin and a step that can be inhibited by a number of factors, including stress, insulin resistance, increasing age, and deficiencies of vitamin C, folate, and iron.
5-HTP is well absorbed when taken orally, with about 70 percent ending up in the bloodstream.*
Intestinal absorption of 5-HTP does not require the presence of a transport molecule and is not affected by the presence of other amino acids; therefore, it may be taken with meals without reducing its effectiveness.* 5-HTP easily crosses the blood-brain barrier and effectively increases central nervous system (CNS) synthesis of serotonin.*
5-HTP has been shown to have a beneficial impact on mood, discomfort associated with fatigue, sleep, and carbohydrate craving.* Numerous studies of individuals with negative mood status have shown significant positive response with 50-300 mg of 5-HTP daily.*
To further facilitate serotonin production, Thorne Research’s 5-HTP formula contains pyridoxal 5′-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin.* 5-HTP is commercially produced by extraction from the seeds of the African plant, Griffonia simplicifolia.
Thorne Research 5-Hydroxytryptophan Ingredients
Vitamin B6 (as Pyridoxal 5′-Phosphate) 6.8 mg.
5-Hydroxytryptophan 100 mg.
Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide. (See manufacturer’s warnings at iHerb.)
Thorne Research 5-Hydroxytryptophan Side Effects
5-Hydroxytryptophan is safe for most users. A search of “5-Hydroxytryptophan side effects” and “5-Hydroxytryptophan reviews” revealed no known side effects. To avoid possible side effects, start with a small dose, and gradually increase to the recommended dosage. Always consult your doctor before taking any supplement.
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