Doctor’s Best SAMe 400 Double-Strength 30 Enteric Coated Tablets 472 Reviews & Coupon*

Doctor’s Best SAMe 400 Double-Strength 30 Enteric Coated Tablets is a natural, SAMe supplement. See 472+ Doctor’s Best SAMe 400 Double-Strength Reviews and save an extra 10% on Doctor’s Best with Coupon Code* YAG250 at

Doctor's Best SAMe 400 Double-Strength 30 Enteric Coated Tablets
Discount: 50%
All Orders: Extra 10% Off
Coupon: Below*
Shipping: Free, Intl. $1.10+
Bottle Size: 30 tablets
Serving Size: 1 tablet
Reviews: 472+
Rating: 4.4

Doctor’s Best SAMe 400 Double-Strength Benefits

Our Double-Strength SAMe 400 contains 400 mg of active SAMe in each tablet. Doctor’s Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none.

S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.

Supplementing with SAMe
The manufacturing process of SAMe yields two forms, the S,S and the R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in Double-Strength SAMe 400 is processed to yield the highest available percentage of the active pure S,S form on the market.

SAMe and Joint Function
SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential components of connective tissue. Clinical studies show an ability of SAMe to enhance mobility and movement, and promote joint comfort.*

SAMe and Neural Health
SAMe-catalyzed methylation reactions promote the synthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function.*

SAMe and Liver Function
SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver protection. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.*

Doctor’s Best SAMe 400 Double-Strength Ingredients

S-Adenosyl Methionine (from 800 mg SAMe tosylate disulfate) 400 mg.

Other Ingredients: Cellulose gel, methacrylic acid copolymer, compritol 888ATO, talc, triethyl citrate, titanium dioxide, magnesium stearate, mannitol, glycerol palmitostearate, silica, medium chain triglycerides, sodium starch glycolate and iron oxide.
The SAMe found in Doctor’s Best SAMe 400 mg (Double Strength) is free from yeast, dairy, gluten, soy, wheat and artificial flavoring.
Contains nothing other than listed ingredients.

Doctor’s Best SAMe 400 Double-Strength Side Effects

SAMe 400 Double-Strength is safe for most users. A search of “S-Adenosyl Methionine side effects” and “S-Adenosyl Methionine reviews” revealed these possible side effects for some users: Upset stomach and nausea. To avoid possible side effects, start with a small dose, and gradually increase to the recommended dosage. Always consult your doctor before taking any supplement.

Compare Doctor’s Best SAMe 400 Double-Strength
30 Enteric Coated Tablets to 27 SAM-e Supplements

Compare 27 SAM-e supplements with 1100+ reviews at: And compare 472+ Reviews for Doctor’s Best SAMe 400 Double-Strength 30 Enteric Coated Tablets. Then save an extra 10% on SAMe 400 Double-Strength with Coupon Code* YAG250

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